PT-141 10mg

PT-141 (Bremelanotide) – 10 mg | For Research Use Only – Not for Human Consumption

PT-141, also known by its research designation Bremelanotide, is a synthetic peptide analog of α-melanocyte-stimulating hormone (α-MSH). Structurally derived from Melanotan II, PT-141 is designed to selectively activate melanocortin receptors, with primary affinity for MC4R and secondary activity at MC1R. This investigational compound is supplied in a 10 mg lyophilized format for preclinical research applications exploring neuroendocrine signaling and immune modulation.

Mechanistic Overview

PT-141 acts centrally via melanocortin-4 receptor (MC4R) stimulation within the hypothalamus, a region implicated in sexual behavior and arousal regulation. Unlike PDE5 inhibitors, which act peripherally on the vasculature, PT-141 directly modulates central nervous system pathways associated with libido and sexual function. In addition to its effects on sexual motivation, PT-141 has demonstrated activity at melanocortin-1 receptor (MC1R), involved in immune modulation and inflammatory regulation.

Preclinical and clinical studies have investigated PT-141’s impact on:

• Sexual arousal and libido enhancement in both male and female models

• Immune system activation, including modulation of innate immune responses

• Vasopressor potential in conditions such as acute hypotension or hemorrhagic shock

Research Applications

PT-141 is used in experimental settings to evaluate:

• Central melanocortin receptor signaling and sexual neuroendocrine pathways

• Hypoactive sexual desire disorder (HSDD) models

• Immune-modulatory effects of melanocortin agonists

• Neuromodulation of arousal states under stress or hormonal suppression

Product Specifications

• Peptide Content: 10 mg (lyophilized)

• Sequence: Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH

• Purity: >98% (validated via HPLC & MS)

• Storage: Store at –20°C; refrigerate reconstituted peptide at 2–8°C

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, or cosmetic.

Bio Peptide Technologies is a chemical supplier. Bio Peptide Technologies is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Bio Peptide Technologies is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.

All products are sold for research, laboratory, or analytical purposes only and are not for human consumption.

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2. All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption