MOTS-c 10mg

For Research Use Only – Not for Human Consumption

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a 16-amino-acid mitochondrial-derived peptide (MDP) that plays a critical role in modulating cellular energy metabolism, insulin sensitivity, and metabolic homeostasis. Encoded within the mitochondrial 12S rRNA region, MOTS-c represents a novel class of signaling molecules that translocate to the nucleus and regulate gene expression in response to metabolic stress.

Mechanistic Insight:
MOTS-c functions by activating AMP-activated protein kinase (AMPK) pathways and influencing genes associated with glucose metabolism, fatty acid oxidation, and cellular resilience. Preclinical models have shown that MOTS-c:

• Enhances insulin sensitivity and glucose uptake in skeletal muscle

• Promotes lipid catabolism and mitochondrial oxidative function

• Inhibits oxidative stress and inflammation under metabolic duress

• Supports cellular adaptation to exercise and metabolic stress

Its effects are consistent with mitochondrial-nuclear communication frameworks, highlighting its potential relevance in aging, sarcopenia, obesity, and type 2 diabetes research.

Research Applications:
MOTS-c is actively being evaluated in experimental models for its implications in:

• Age-associated metabolic dysfunction

• Insulin resistance and glucose dysregulation

• Obesity and mitochondrial inefficiency

• Exercise physiology and adaptive performance

• Mitochondrial signaling and longevity mechanisms

These findings position MOTS-c as a highly promising peptide for studying mitochondrial-derived regulators of systemic energy balance and genomic expression reprogramming in response to stress.

Analytical Quality and Validation:
Each batch of MOTS-c is synthesized under strict quality standards and verified via high-performance liquid chromatography (HPLC) and mass spectrometry (MS) to ensure structural integrity, purity, and reproducibility for investigative use.

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, or cosmetic.

Bio Peptide Technologies is a chemical supplier. Bio Peptide Technologies is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Bio Peptide Technologies is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.

All products are sold for research, laboratory, or analytical purposes only and are not for human consumption.

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1. Research Use Only: All products provided by Bio Peptide Technologies are intended solely for in-vitro laboratory research purposes. These materials are expressly forbidden for any form of human or animal use, ingestion, or administration.

The products offered on this platform are not formulated, designed, or intended to diagnose, cure, mitigate, treat, or prevent any diseases or medical conditions.

2. All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption.