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IGF-1 LR3 1mg

IGF-1 LR3 1mg

by Biopeptitech
$99.00 - $99.00
$99.00
$99.00 - $99.00
$99.00

IGF-1 LR3 – 1 mg | For Research Use Only – Not for Human Consumption

IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg³) is a synthetic analog of human IGF-1, engineered with a 13-amino acid N-terminal extension and a substitution of arginine for glutamic acid at position 3. These structural modifications confer a significantly prolonged half-life (up to 20–30 hours in vivo) and markedly reduced affinity for IGF-binding proteins (IGFBPs), resulting in enhanced bioavailability and sustained biological activity.

Mechanistic Overview

IGF-1 LR3 exerts its effects by binding to the IGF-1 receptor (IGF1R), a transmembrane tyrosine kinase receptor that activates PI3K/Akt and MAPK/ERK signaling pathways. These cascades are essential in regulating cell proliferation, differentiation, protein synthesis, and apoptosis suppression.

In preclinical research, IGF-1 LR3 has been shown to:

  • Stimulate myoblast proliferation and muscle cell differentiation

  • Promote skeletal muscle hypertrophy and regeneration following injury

  • Enhance lipolysis and influence fat metabolism

  • Support mammary gland development and lactation in animal models

  • Facilitate anabolic recovery in GH-deficient states and catabolic conditions

Research Applications

IGF-1 LR3 is employed in in vitro and in vivo experimental models to investigate:

  • Growth factor signaling pathways and tissue regeneration

  • Muscle wasting, cachexia, and sarcopenia

  • Adipose metabolism and body composition regulation

  • Lactogenesis and hormonal interactions in mammary tissue

  • Age-associated anabolic resistance and cellular senescence

Its enhanced receptor activity and reduced IGFBP interference make IGF-1 LR3 a valuable agent for studying long-acting growth factor effects across physiological systems.

Product Specifications

  • Peptide Content: 1 mg (lyophilized)

  • Molecular Weight: ~9.2 kDa

  • Purity: >98% (validated via HPLC & MS)

  • Storage: Store lyophilized at –20°C; refrigerate reconstituted solution at 2–8°C and use within designated research window

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, or cosmetic.

Bio Peptide Technologies is a chemical supplier. Bio Peptide Technologies is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Bio Peptide Technologies is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.

All products are sold for research, laboratory, or analytical purposes only and are not for human consumption.

YOU MUST BE OVER 21 YEARS OLD TO USE THIS WEBSITE.

1. Research Use Only: All products provided by Bio Peptide Technologies are intended solely for in-vitro laboratory research purposes. These materials are expressly forbidden for any form of human or animal use, ingestion, or administration.

The products offered on this platform are not formulated, designed, or intended to diagnose, cure, mitigate, treat, or prevent any diseases or medical conditions.

2. All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption