FOXO4-DRI 10mg
FOXO4-DRI 10 mg
Research Compound
For Research Use Only. Not for Human Consumption.
Product Overview
FOXO4-DRI is a research-grade synthetic peptide developed for laboratory investigation of cellular senescence, protein interactions, and programmed cell death. Its D-retro-inverso structure incorporates a reversed amino-acid sequence with D-amino acids, a design used to improve resistance to enzymatic degradation.
FOXO4-DRI is studied for its ability to interfere with the interaction between Forkhead box protein O4 (FOXO4) and the tumor-suppressor protein p53. In experimental models, disruption of this interaction can alter p53 localization and promote apoptosis in senescent cells. These characteristics make it a compound of interest in research involving senolytic mechanisms, cellular stress responses, and senescence-associated signaling.
Findings from cell and animal studies do not establish safety or therapeutic benefits in humans.
This product is intended exclusively for research, analytical, and educational applications.
Research Characteristics
Researchers commonly investigate:
✔ Molecular structure and peptide composition
✔ Cellular senescence mechanisms
✔ FOXO4–p53 protein interactions
✔ p53 localization and signaling
✔ Apoptosis regulation
✔ Senolytic activity in experimental models
✔ Senescence-associated secretory phenotype (SASP)
✔ Cellular stress-response mechanisms
✔ Peptide stability characteristics
✔ Structure-function relationships
✔ Analytical laboratory methodologies
Product Specifications
Compound: FOXO4-DRI
Research Identifier: FOXO4 D-Retro-Inverso peptide
Strength: 10 mg per vial
Peptide Length: 46 amino acids
CAS Number: 2460055-10-9
Molecular Formula: C₂₂₈H₃₈₈N₈₆O₆₄
Molecular Weight: 5358.06 g/mol
Reference Form: FOXO4 D-retro-inverso peptide; molecular formula and weight exclude counterions
Formulation: Lyophilized Powder
Grade: Research Grade
Purity: Refer to batch-specific Certificate of Analysis (COA)
Storage: Follow batch-specific storage instructions and the Safety Data Sheet (SDS)
Testing: Refer to batch-specific COA for analytical methods and results
Intended Use: Research Use Only
Important Disclaimer
For Research Use Only.
This product is not intended for human consumption, medical use, therapeutic use, diagnostic use, veterinary use, or as a food additive.
The statements on this website have not been evaluated by the Food and Drug Administration (FDA).
Purchasers are responsible for ensuring compliance with all applicable laws and regulations governing the use of research materials.