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Tesamorelin 10mg

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Original price $89.99
Original price $89.99 - Original price $89.99
Original price $89.99
Current price $70.00
$70.00 - $70.00
Current price $70.00
13.0oz | $5.38 / oz

Tesamorelin – 10 mg | For Research Use Only – Not for Human Consumption

Tesamorelin is a synthetic peptidyl analog of growth hormone-releasing hormone (GHRH 1–44), engineered to resist degradation by dipeptidyl peptidase IV (DPP-IV) and extend its biological half-life. This stabilized GHRH analog selectively binds to GHRH receptors on pituitary somatotrophs, inducing endogenous pulsatile growth hormone (GH) secretion and subsequently elevating insulin-like growth factor-1 (IGF-1) levels.


Mechanistic Overview

Tesamorelin activates the hypothalamic-pituitary-somatotropic axis, enhancing GH release and downstream IGF-1 production, both of which regulate lipid metabolism, protein synthesis, and neuronal support functions. Its enhanced pharmacokinetics and receptor specificity make it a powerful tool for evaluating GH-mediated physiological and metabolic responses in research models.

Preclinical and experimental studies have shown Tesamorelin to:

  • Stimulate lipolysis and reduce visceral adipose tissue accumulation

  • Improve glucose and lipid metabolic parameters

  • Enhance peripheral nerve integrity and myelin repair mechanisms

  • Modulate neuronal plasticity and cognitive function through IGF-1–related pathways

  • Exhibit neuroprotective effects in models of age-related cognitive decline


Research Applications

Tesamorelin is studied in in vitro and in vivo models for its potential in:

  • GH deficiency and metabolic syndrome research

  • Visceral adiposity and lipodystrophy models

  • Peripheral neuropathy and neuroregeneration

  • Cognitive aging and neurodegenerative disease pathways

  • GH/IGF-1 axis modulation in systemic aging models

Its dual relevance in metabolic regulation and neuroendocrine health positions Tesamorelin as a valuable investigational compound in regenerative and therapeutic peptide research.


Product Specifications

  • Peptide Content: 2 mg (lyophilized)

  • Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Gly-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH₂

  • Purity: >98% (validated by HPLC & MS)

  • Storage: Store lyophilized at –20°C; reconstituted solution should be refrigerated at 2–8°C