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Sema 10mg

Sema 10mg

by Biopeptitech
$150.00 - $150.00
$150.00
$150.00 - $150.00
$150.00

For Research Use Only – Not for Human Consumption

Sema is a long-acting, research-grade GLP-1 receptor agonist structurally derived from the endogenous incretin hormone glucagon-like peptide-1 (GLP-1). Designed to resist enzymatic degradation via DPP-4 cleavage, Sema exhibits an extended half-life, allowing for once-weekly administration in clinical research models. Its molecular structure incorporates amino acid substitutions and a fatty acid side chain to facilitate albumin binding and prolong systemic circulation.

Mechanistic Profile:
Sema exerts its biological effects through GLP-1 receptor (GLP-1R) activation, leading to:

  • Glucose-dependent insulin secretion from pancreatic β-cells

  • Suppression of glucagon release from α-cells

  • Delayed gastric emptying and reduced gastrointestinal motility

  • Central appetite regulation via hypothalamic signaling

Preclinical Investigations have demonstrated its potential to improve glucose tolerance, enhance β-cell function, and modulate satiety pathways. Emerging animal and cellular studies suggest broader investigational applications in the context of:

  • Cardiovascular remodeling and endothelial function

  • Hepatic lipid metabolism and steatosis

  • Pulmonary inflammation and fibrosis attenuation

  • Neuroinflammation and amyloid deposition in Alzheimer’s disease models

Research Applications:
Sema is under active investigation in preclinical settings to assess its role in:

  • Metabolic disorder modeling (e.g., type 2 diabetes, obesity)

  • Neurodegenerative disease pathways

  • Gut-brain axis signaling mechanisms

  • Incretin-based regenerative and organ-protective strategies

Quality Assurance:
Each lot of Sema is synthesized to rigorous analytical specifications and undergoes HPLC and MS validation to confirm identity, purity, and bioanalytical consistency for reproducible experimental results.

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, or cosmetic.

Bio Peptide Technologies is a chemical supplier. Bio Peptide Technologies is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Bio Peptide Technologies is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.

All products are sold for research, laboratory, or analytical purposes only and are not for human consumption.

YOU MUST BE OVER 21 YEARS OLD TO USE THIS WEBSITE.

1. Research Use Only: All products provided by Bio Peptide Technologies are intended solely for in-vitro laboratory research purposes. These materials are expressly forbidden for any form of human or animal use, ingestion, or administration.

The products offered on this platform are not formulated, designed, or intended to diagnose, cure, mitigate, treat, or prevent any diseases or medical conditions.

2. All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption.